Isosorbide mononitrate - UpToDate It can make you really dizzy. This is so your doctor can check on your progress. Isosorbide mononitrate systemic 60 mg (A ID). For haemoglobin formation vit. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. Try our Symptom Checker Got any other symptoms? Your doctor may tell you to take a pain reliever to treat your headaches. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. You may report side effects to the FDA at 1-800-FDA-1088. Natural Medicines. Many common herbal supplements interact with common heart medicines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. It can cause your blood pressure to become dangerously low. Real test is coronary angiography. . Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. include protected health information. Store at room temperature away from light and moisture. https://naturalmedicines.therapeuticresearch.com. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. https://naturalmedicines.therapeuticresearch.com. Are you looking for information on isosorbide dinitrate (Isordil) instead? Do not take a double dose to make up for a missed one. It is best not to drink alcohol while you are on isosorbide mononitrate. Use this medication regularly to get the most benefit from it. Always consult your healthcare provider. Isosorbide mononitrate helps to prevent angina chest pain from developing. Avoid combinations; the risk of the interaction outweighs the benefit. Click here for an email preview. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Even if the medication is working, you may experience some unwanted side effects. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. https://naturalmedicines.therapeuticresearch.com. 7 disease interactions. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. This is called a medicine interaction. WebMD does not provide medical advice, diagnosis or treatment. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. There are 195 drugs known to interact with Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Isosorbide mononitrate helps to prevent angina chest pain from developing. Many people using this medication do not have serious side effects. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Copyright 2023 IBM Watson Health. Overview of herbal medicines and dietary supplements. Continue to take isosorbide even if you feel well. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Accessed Sept. 7, 2022. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Natural Medicines. Take your next dose at the regular time. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Isosorbide mononitrate helps to prevent angina chest pain from developing. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Some don't work well with prescription medicines. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Keep all medications away from children and pets. eCollection 2021. Isosorbide - StatPearls - NCBI Bookshelf Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. I took this for 4 days, and my headaches were unbearable. This medication belongs to a class of drugs known as nitrates. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Cleophas TJ, Niemeyer MG, van Der Wall EE. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Ginkgo. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. Using this medicine with any of the following medicines is not recommended. The most common side-effect is headache. Does Isosorbide Mononitrate interact with other medications? Does Viagra add to the risks of melanoma? Headache and weakness of left side (both arm and leg) may suggest a brain pathology. Natural Medicines. If you have any questions about this medicine ask your pharmacist. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Sept. 26, 2022. Changing positions slowly can help lessen dizziness. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. UpToDate 2017; doi:10.1016/j.jacc.2016.11.078. This does not necessarily mean no interactions exist. Epub 2006 Mar 22. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). This is not a complete list of possible side effects. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Herbal medications in cardiovascular medicine. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Consult your pharmacist or local waste disposal company. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. View interaction reports for isosorbide mononitrate and the medicines listed below. It is important to take the drug at the same times each day. Accessed Sept. 7, 2022. Isosorbide is in a class of medications called vasodilators. Daily headaches are a common side effect. Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Take isosorbide exactly as directed. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Do not stop taking isosorbide without talking to your doctor. This product may contain inactive ingredients, which can cause allergic reactions or other problems. B12 and folic acid is essential along with iron. Consult your doctor before breast-feeding. May also be prescribed off label for Esophageal Spasm. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. If headaches continue or become severe, tell your doctor promptly. Prescription and OTC 67% of reviewers reported a positive effect, while 13% reported a negative effect. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Mayo Clinic does not endorse companies or products. Select a condition to view a list of medication options. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. https://naturalmedicines.therapeuticresearch.com. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Data were assessed for carryover and time effects. The table below contains some of the most common ones associated with isosorbide mononitrate. https://naturalmedicines.therapeuticresearch.com. Diabetes treatment: Can cinnamon lower blood sugar? These headaches may be a sign that the medication is working as it should. sharing sensitive information, make sure youre on a federal Isosorbide Mononitrate - Uses, Side Effects, and More - WebMD You can take your doses either before or after meals. Available for Android and iOS devices. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). AHFS Patient Medication Information. Aspirin relieves pain and inflammation and helps to thin the blood. Some side effects may occur that usually do not need medical attention. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. A very serious allergic reaction to this drug is rare. Take this medication by mouth as directed by your doctor, usually twice a day. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Don't drink alcohol while taking isosorbide mononitrate (Monoket). It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Medicines containing Isosorbide Mononitrate. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. Advertising revenue supports our not-for-profit mission. Journal of the American College of Cardiology. Dehydration in Buspar, how severe and when it was recovered? Results: Isosorbide mononitrate - Wikipedia These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). information and will only use or disclose that information as set forth in our notice of Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Talk to your provider if you notice your chest pain starts to get worse. View more. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. Integrative medicine (complementary and alternative medicine). May also be prescribed off label for Esophageal Spasm. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. On the other hand, the ER version can only help prevent angina. Of the total drug interactions, If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Liperoti R, et al. It might help to take isosorbide mononitrate and dinitrate after meals. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. The tablet usually is taken two or three times daily. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Enter other medications to view a detailed report. What should I know about storage and disposal of this medication? This is called tolerance, and it cannot be fixed by raising the dose of the medication. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). The site is secure. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Nitrate-induced headache in patients with stable angina pectoris In: Current Medical Diagnosis & Treatment 2022. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). No, that's not true all the time. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? isosorbide mononitrate prices. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide Manufacturing: An In-Depth Look at Production Costs and My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Available for Android and iOS devices. See the full pregnancy warnings document. If you miss a dose, take it as soon as you remember. It does not have such side effects. Accessed Sept. 7, 2022. This medicine is for you. Isosorbide dinitrate dose 30-120 mg daily in divided doses. What are the side effects of Isosorbide Mononitrate ? Journals of the American College of Cardiology. What happens if I stop taking isosorbide mononitrate (Monoket)? 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Accessed Sept. 7, 2022. Consult your doctor for more details. Methods: See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. This medicine is available only with your doctor's . Conclusions: It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. It works to relax your blood vessels. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Herbal supplements can strongly affect the body. St. John's wort. Would you like email updates of new search results? daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. I would rather take the chance of a heart attack than have no quality of life. Instead, the best way to dispose of your medication is through a medicine take-back program. HHS Vulnerability Disclosure, Help